Arizona Cardinals right guard Isaiah Adams appeared on the first injury report for the team's Week One matchup against the Chargers. The report indicated that Adams did not participate in practice sessions. If the 27-year-old player cannot make progress in the two days leading up to the game, backup guard Jon Gaines II is expected to take his place at the starting position.
Gaines, who stands 6 feet 4 inches and weighs 303 pounds, has accumulated five career starts since entering the league. He was selected in the fourth round of the 2023 draft out of UCLA. In the 2025 season, Pro Football Focus assigned Gaines a 60.3 overall grade, ranking him 43rd among 81 guards.
The Cardinals' official website noted that quarterback Jacoby Brissett is described as being "rich with respect" from his teammates. Additionally, the team shared links to betting odds and prop bets for the upcoming contest.
Broader NFL news items mentioned in the report include Sam Darnold receiving confirmation that he does not have a fractured hip, and Drew Lock stepping in for Darnold to help the Seattle Seahawks secure a victory over New England.
